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Pepcid AC is used to relieve heartburn symptoms associated with indigestion Some people have long-term side effects from taking famotidine. 20 mg twice daily; or 40 mg twice daily. Mar 11, · Drugs you may obtain without a prescription are referred to as “OTC” drugs which means over-the-counter Over The Counter Vs. It works by blocking the production of acid by acid-producing cells in the stomach. 1 year or as clinically indicated Pepcid (famotidine) is an H2-blocker and Prilosec is a proton pump inhibitor (PPI). My vet was in emergency surgery and I was heading to work In general, you can take over-the-counter (OTC) famotidine (Pepcid AC, Zantac 360) at any time of the day or night to help treat heartburn symptoms. Maintenance Therapy: The recommended adult oral dose is 20 mg once a day at. 1 year or as clinically indicated Pepcid (famotidine) is an oral drug that belongs to a family of drugs called H2 blockers. These drugs effectively treat about ½ the patients with GERD. 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